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` F򗝂Ǝ.11F4327, 1983.!10.qh FbƗՏ.24F6955, 1990.!11.cW FVƗ.39F2485, 1990.!12.쓇N FVƗ.39F2238, 1990.!13.˕q F򗝂Ǝ.19F339, 1991.!14.–؏Ɩ FwƖw.25F233, 1991.!15.˕q FfÂƐV.27F2235, 1990.!16.–؏Ɩ FwƖw.25F499, 1991.!17.˕q FfÂƐV.28F1, 1991.!18.˕q FfÂƐV.28F13, 1991.!19.} FwƖw.24F1293, 1990.!20. FbƗՏ.20F9161, 1986.!21.ʈ䒼 FՏ.18F553, 1987.!22. F.36F592, 1987.!23.]c Fȕ.30F365, 1983.!24.]c Fȕ.31F11, 1984.!25.nmO F򗝂Ǝ.11F3637, 1983.!26.ODHn FbƗՏ.17F2909, 1983.!27.ODHn FbƗՏ.17F2917, 1983.!28.]c Fȕ.31F51, 1984.!29.rYv F{awG.80F694, 1983.!30.Miwa, M.et al.FInt. J. Clin. Pharmacol. Ther. Toxicol.22F214, 1984.!31.{{Y F򗝂Ǝ.11F3651, 1983.!32.X F7񐢊Eaw\.!33. FfÂƐV.20F1859, 1983.!34.吼vmF F򗝂Ǝ.11F4301, 1983.!35.ODHn FVƗ.32F1383, 1983.!36. FՏla.14F571, 1984.!37.|c FbƗՏ.17F2878, 1983.!38.Takeda, M. et al.FEur. J. Pharmacol.91F371, 1983.!39.Takagi, T. et al.FArch. Int. Pharmacodyn.256F49, 1982.!40.|c FbƗՏ.18F6125, 1984.!41.co FbƗՏ.25F223, 1991.!42.Takeda, M. et al.FArzneim-Forsch.32F734, 1982.!43.Ishihara, Y. et al.FDigestion.27F29, 1983.",*AXeX򊔎�,Տpʂł̃p[^!\Jn!; pʁimgj; Tmaxihj; Cmaxing/mLj; ihj; AUCingEh/mLj;!Ò; 20; \; \; 2.45; 771;!ؒ; 20; 0.411; 265; 2.66; 686;!\I,Տ(1)㕔ǏoyZollinger-EllisonnjQ!Ö^ɂʗՏi53jApʌi84jAdӌri59jyыؓ^ɂʗՏi33jAv229̊Tv͎̂Ƃł遣7`10jB㕔ǏoF~!Ö^ɂ~ʂ91.2i165/181jAdӌrɂĖ{܂̗LpF߂ꂽBpʌyѓdӌrɂ120mgA12Ö^ł̎~ʂ91.0i91/100jŁA^36Ԉȓ̎~66.0i66/100jA3ȓ̎~84. 0i84/100jłB܂Aؓ^ɂĂAÖ^Ƃقړ̎~ʕтɗLpF߂ꂽB!㕔ǏoF~ێ!Ö^ł̎~o^i120mg12jɂ~ێʂ͗ǍDłB!Zollinger-EllisonnjQ!ʗՏ6ᒆio^5AÖ^1jA5io^4AÖ^1jɗLłB!(2)NPXgXipɏWǗKvƂpAWÂKvƂ]ǏQEOEsSEL͈͔Mjɂ㕔Ǐo̗}!Ö^ɂʗՏi85jA pʌi189jA dӌri209jAyыؓ^ɂʗՏi36jAv519̊Tv͎̂Ƃł遣11`19jBNPXgXɂ㕔Ǐo̗}!pAWÂKvƂ]ǏQEOEsSEM̐NPXgXɂݎ_̘i}邱ƂړIƂՏɂ120mgA12Ö^ł̗L77.4i250/323jAdӌrɂĖ{܂̗LpF߂ꂽB!܂Aؓ^ɂʗՏɂĂAÖ^Ƃقړ̗LyїLpF߂ꂽB!(3)O!ؓ^ɂʗՏi23jAӌri79jAdӌri132jyѐÖ^ɂӌri81jAv315̊Tv͎̂Ƃł遣20`22jBO!ɂ뚋x̖h~ړIƂdӌr܂ޗՏɂāA{܂120mgAؓ^yѐÖ^̂ɂĂALӂɈ݉tʂA݉tpH㏸B!̗L80.1i241/301jłBdӌrɂėLpF߂ꂽB,,"1.qgł̍p1.ݎ_yуyvV}p1)byъeh!l͏ᇊ҂ɂAbyъehܓ^2Ԉݎ_yуyvVʂ́A20mgo^ɂ肻ꂼ71.6`99.6A29.5`96.9}B!܂A20mgÖ^ŊbAegKXgAx^][h}遣26, 27jB!2)ԕ偣28j!l͏ᇊ҂̌ߌ11ߑO6܂ł7Ԉݎ_yуyvVʂ́A20mgo^ɂ肻ꂼ91.8A71.8}B!3)24ԕEݓpH29j!l̈ݎ_ʂ́A20mgo^ɂAߌ812Ԉȏɂ킽}A12Ԉݎ_}93.8łBݓpH́A^1Ԍɂ4ȏƂȂA12Ԍ܂5`6͈̔͂ŐڂB!4)Zxƈݎ_}p30j!Zxƈݎ_}Ƃ̊Ԃɂ͐̑֊֌W݂Aݎ_ʂ50}Ƃ̌Zx13ng/mLłB2.ݔSʂɋyڂe31j!0. 1`0.2mg/kg̐Ö^ł͌l̈ݔSʂ𑝉XF߂B!3.ݔStɋyڂe32j!\wᇊ҂̈݉tStZxɉeyڂȂB!4.ݓero\ɋyڂe33j!ݒᇁA\wᇊ҂20mgo^ꍇAݔro\ɉeyڂȂB!5.̌sԂɋyڂe34j!20mgÖ^́Al̊̌ʁA喬ʂɉeyڂȂB!6.KXglɋyڂe35j!ݒᇁA\wᇊ҂20mg12A1`2Jo^ꍇAKXglɉeyڂȂB!7.vN`ɋyڂe36j!20mgÖ^A20mg124TԌo^́AlAᇊ҂̌vN`ABhzAzlɉeyڂȂB!2.ł̍p1.H2e̝hRp37, 38j!bgEoS[̐SAbgEoq{̎kACk̈ݎ_wWɂH2e̝hRṕAV`Wɔ䂵10`148{͂łB!2.ݎ_}p39`41j!Ck̃qX^~ḧݎ_}ʂ́AV`Wɔ䂵pxŖ40{AԂŖ1.3`1.5{B!܂Abg̊eNPXgXɂݎ_}ʂ́A_s[sƓ邢͂⋭AV`WA_j`W苭B!3.ݔStɋyڂe40j!bg̃XgXɂݔS񔒗ʂ̌Lӂɗ}B!4.ᇂɑ΂p42, 43j!bg̃Ch^VAAXsAvhj]AXgXyїH匋Fɂݒᇂ邢̓VXeA~yуs][ɂ\wᇂ̔ɑ΂ăV`W}ʂB܂AA^ɂ|_ɂݒᇋyуs][ɂ\wᇂ̎𑣐iA͂̓V`W苭B!5.ݏoɑ΂p40j!EyуqX^~^ɂ郉bg̈ݏoɑ΂}pB!3.S. G. et al.FAliment. Pharmacol. Ther.7F317, 1993.!4.Г񍐏F D9502069-1, 1986.!5.Г񍐏F D9602641-1, 1987.!6.Г񍐏F D200401523-1, 2003.!7.鏊 F򗝂Ǝ.11F3659, 1983.!8.ODHn FfÂƐV.20F2123, 1983.!9.` F򗝂Ǝ.11F4327, 1983.!10.qh FbƗՏ.24F6955, 1990.!11.cW FVƗ.39F2485, 1990.!12.쓇N FVƗ.39F2238, 1990.!13.˕q F򗝂Ǝ.19F339, 1991.!14.–؏Ɩ FwƖw.25F233, 1991.!15.˕q FfÂƐV.27F2235, 1990.!16.–؏Ɩ FwƖw.25F499, 1991.!17.˕q FfÂƐV.28F1, 1991.!18.˕q FfÂƐV.28F13, 1991.!19.} FwƖw.24F1293, 1990.!20. FbƗՏ.20F9161, 1986.!21.ʈ䒼 FՏ.18F553, 1987.!22. F.36F592, 1987.!23.]c Fȕ.30F365, 1983.!24.]c Fȕ.31F11, 1984.!25.nmO F򗝂Ǝ.11F3637, 1983.!26.ODHn FbƗՏ.17F2909, 1983.!27.ODHn FbƗՏ.17F2917, 1983.!28.]c Fȕ.31F51, 1984.!29.rYv F{awG.80F694, 1983.!30.Miwa, M.et al.FInt. J. Clin. Pharmacol. Ther. Toxicol.22F214, 1984.!31.{{Y F򗝂Ǝ.11F3651, 1983.!32.X F7񐢊Eaw\.!33. FfÂƐV.20F1859, 1983.!34.吼vmF F򗝂Ǝ.11F4301, 1983.!35.ODHn FVƗ.32F1383, 1983.!36. FՏla.14F571, 1984.!37.|c FbƗՏ.17F2878, 1983.!38.Takeda, M. et al.FEur. J. Pharmacol.91F371, 1983.!39.Takagi, T. et al.FArch. Int. Pharmacodyn.256F49, 1982.!40.|c FbƗՏ.18F6125, 1984.!41.co FbƗՏ.25F223, 1991.!42.Takeda, M. et al.FArzneim-Forsch.32F734, 1982.!43.Ishihara, Y. et al.FDigestion.27F29, 1983.",*AXeX򊔎�̕tĂ铊, @FՌEۑ!gpFOɕ\igp3Nj,1.{܂̐ɑ΂ߕqǂ̊̂銳!2.ǂ̂֐ߍoAtXAFF́mƉorc[_Upxs;!^; ֐߂̕s艻i֐ߍoˎj1AuɁEEɂ̑i֐ߍoˎjAǏgD̈ޏkɂזvi͔ؓˎj;!n; oُANbVOnjQlǏ;!; ASEqfAݒɁA₯AcAAH~sUAH~i;!__on; KǁAsAɁA߂܂;!؁Ei; ؓɁA֐ߒɓ;!E`; leA싍AftAb̓;!̉tEd; A㏸AJEAJ[VX;!; ԖQAዅˏo;!t; ;!畆; ጁAсAEсAFfA牺쌌AAAyAُAʍgAbD;!̑; MAJAXeChtǁȀdAqyт̉^̑AAH΁AnQA畆EgDɔEƎ㉻;!\I!1: Ǐ󂪂ꂽꍇɂ͓^𒆎~邱ƁB̏Ǐ͓^ɊƋN₷ƂĂ̂ŁA^͊҂΂炭Âɂ邱ƁB,,҂ɒ^ꍇAǂ̗UAAaAe頏ǁAǁAXAΓᓙ̕p₷̂ŁATdɓ^邱ƁB,1.Dw͔DPĂ"\̂wlɂ́AÏ̗Lv댯Ɣfꍇɂ̂ݓ^邱ƁBmibg2)A}EX3)AETM4)AnX^[5)jōÊ`p񍐂ĂA܂AVɕtsSNƂBn!2.̕wlɂ͖{ܓ^͎邱ƁBmֈڍs邱ƂBn,1.ȍdAVAAc͏̔}邱Ƃ̂ŁA�3A4ł遣8)9)B,\1 򕨓ԃp[^!\Jn!Ώ; n; Cmaxing/mLj; AUCingEhr/mL); T1/2ihrj; VDSS(L); CLt(mL/min);!Nl; 12; 481}81; 2578}621; 3.17}0.44; 26.7}3.6; 102}23;!͊; 7; 535}56; 3982}9811; 4.74}0.992; 26.5}1.6; 66}171;!\I!1: NlƗLӍp0.01iWilcoxon testj!2: NlƗLӍp0.05!al.FPediatr.Res.,15,19(1981jk198101672l!3.Pinsky,L.et al.FScience,147,402(1965jk200401965l!4.Walker,B.E.FProc.Soc.Exp.Biol.Med.,125(4),1281(1967jk196700167l!5.Shah,R.M.et al.FJ.Embryol.Exp.Morph,36(1),101(1976jk200401966l!6.{nKقFffƎÁA64(6),944(1976jk197600598l!7.Bergrem,H.

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FKidney International,23,876(1983jk198302389l!8.tFÁA76(9),2214(1994)k199401231l!9.{BjFXeChzieҁjApp.50-51AOwЁA(1988)",`򊔎�5200123D1028,I[XMbSGLXf,ʏAl17.5g2`3ɕAHO͐HԂɌo^BȂANȀdAǏɂKXB,݂‚AƂɈSEqfAH~sUŕ‚ēւ܂͉̌X̂̎̏ǁF}EݒJ^AyAsǁA݉A_o݉AݎAAՁA₯AA_oAALT(GPT)AAl|PA|GTP̏㏸𔺂�Tab.200mg,*2007N6,2001N10,,wi,Eܗʁi1j!{�AUC0-24hr!(gEhr/mL); Cmax!(g/mL); Tmax!(hr);!A_200mg; 14.99}1.31; 7.74}0.95; 1.3}0.2;!W; 16.46}1.11; 8.30}0.79; 1.4}0.2;!\I!(Mean}S.E.An20),,,N[̋؂̗k}ƋɁANxz_o(Ր_oA_o)̋ɂNkɉB܂N؂ɑ΂Ca2{}AzXzWGXe[[jQɂcAMPɂoɍpB̍pԓx͍RRppxƂ͖炩ɈقȂA؂ɑ΂Ăْ͂̋ۂArA͂ቺ邱ƂȂArA͂ێ遣3)B,ʖ!kǁlt{LT[g_(Flavoxate Hydrochloride)!kǕʖl_t{LT[g!w!2-(Piperidin-1-yl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate monohydrochloride!q!C24H25NO4EHCl!q!427.92!\!!{i͔F̌͌̕łB!{i͐|_(100)̓NzɂnɂA̓G^m[(95)ɗnɂAAZgjg̓WG`G[eɂقƂǗnȂB,*萫!ŏIipĉi40AΎx75A6j{ʁAA_200mg͒ʏ̎sꗬʉɂ3NԈł邱Ƃꂽ4)B,,PTC-3629AA쏑X!4.iKZi()FA_200mg̈�vol!{Ǖ_f!50 vol,,,_fE_f,,,,,,,,1.r^~a12̕sɂ� !_fiNitrous OxidejiJANj! w !_fiNitrous Oxidej! q !m2n! q !44.01,,"2,000L!8,000L","1.b F؂ƖA43(12)F100 (1976)!2.䖾aFYwA4(1)F335i1974j!3.p FYwlȂ̐EA28(8)F77 (1976)!4.l B F{ΎVA2576F13 (1973)!5.Eastwood, Douglas. W.FClinical Anesthesia (nitrous oxide)F21 (1964)!6.ؒF{ȖwA2(1)F25 (1974)!7.䗘aFA9(7)F476 (1960)!8.RGvFA8(3)F211 (1959)!9.Lassen, H. C. A.FLancetA270F527 (1956)!10.Green, C. D.FClinical Anesthesia (nitrous oxide)F38 (1964)!11.Parbrook, G. D.FBrit. J. Anaesth.A39F730 (1967)!12.Parbrook, G. D.FBrit. Med. J.A2F480 (1964)!13.Parbrook, G. D.FBrit. J. Anaesth.A39F119 (1967)!14.Fink, B. R., et. al.FNatureA 214F146 (1967)!15.{wFA32(9)F1136 (1983)!16.Baird, P. A.,FThe New England Journal of MedicineA 327(14)F1026 (1992)!17.Rowland, A. S., et al.FThe New England Journal of MedicineA327(14)F993 (1992)!18.XcV F40k{Ȋwv|, p.52 (2002)!19.Yang, Y. F., et al.:Brit. Med. J., 325F532 (2002)",**adH�(nA)̂銳ҁmǏ邨ꂪBn,1.ߕqǏ󓙂\邽߁A\ȖfsƁB!2.ƂĒ^邱ƁB,,,,,,,,,,,{܂͎gpђ̕ppxmƂȂ钲{ĂȂB,,1.VbN!(pxs)!VbNǏ󂪂邱Ƃ̂ŁA�2),,,,,*XeChɍ܂𒷊ԓ^Ă鏗ɂāAꎞIȕsDF߂ꂽƂ̕񍐂B,,,,,{̓A`sƃJtFC̑pŒɌʂ߂̂ŁAɕГɂɌʓIłBA`s͎ɍpAɊo`BH̋SVivX̊󐫂ቺ邱Ƃɂu臒l㏸AɍpB܂JtFĆA̒ɍp̂قA]ǒR𑝑債A]ʂ邱ƂɂAɂpB,"ʖF!~Oj (Migrenin)!F!{i͔F͌̕̕ŁAɂ͂ȂA͋ꂢB{i͐ɋɂ߂ėn₷AG^m[(95)̓Nzɗn₷AWG`G[eɗnɂB!{i1.0g10mLɗntpH3.0`4.0łB!{i͎CyьɂĕωB!Z_F!104`1101.A`sʖF!A`s (Antipyrine)!wF!1, 5-Dimethyl-2-phenyl-1, 2-dihydropyrazol-3-one!w\F!qF!C11H12N2O!qʁF!188.23!Z_F!111`113!F!{i͖FႵ͔F̌͌̕ŁAɂ͂ȂA͂킸ɋꂢB!{i͐ɋɂ߂ėn₷AG^m[(95)ɗn₷AWG`G[eɂnɂB!{i̐nt(110)͒łB!2.JtFCʖF!JtFC (Caffeine)!wF!3, 7-Dihydro-1, 3, 7-trimethyl-1H -purine-2, 6-dione monohydrate!w\F!qF!C8H10N4O2EH2O!qʁF!212.21!Z_F!235`238 ()B!F!{i͔F̏_炩͕ŁAɂ͂ȂA͂ꂢB{i̓Nzɗn₷AA|_(100)͖|_ɂnɂAG^m[(95)ɗnɂAWG`G[eɋɂ߂ėnɂB{i1.0g100mLɗntpH5.5`6.5łB!{i͊CŕB!3.NG_ʖF!NG_ (Citric Acid)!wF!2-Hydroxypropane-1, 2, 3-tricarboxylic acid monohydrate!w\F!qF!C6H8O7EH2O!qʁF!210.14!F!{i͖F͔̌F̗Ⴕ͌̕ŁAɂ͂ȂA_B!{i͐ɋɂ߂ėn₷AG^m[(95)̓AZgɗn₷AWG`G[eɂnɂB!{i͊CŕB",zω!{͍ExɕۑƋz₷A܂A̖򕨂Ƃ̍ŗZ_~AՊEx̒ቺN₷B,,500g,"1.ԘavF eRǍ܂ِ̑ǎkɊւ铮 (\)!2.Ԙav F Ȃ̐i, 2, 95 (1983)!3.\l{Ǖ (A쏑X)",VIG򊔎�supp.,1981N11,1981N11,{ǕFCh^V,!wi!*iFӁ|t̏ɂgp邱ƁB,Eܗ (1')!{ǕCh^V 12.5mg!Y!n[h^ꍇɂ́AIɗՏ(AAtyъȓI)sƁB܂Aُ킪F߂ꂽꍇɂ́AʁAx򓙂̓K؂ȑ[uu邱ƁB!C.򕨗�AST(GOT)㏸AALT(GPT)㏸ )!__on4)!(pxs)!JA_oߕqAsAlǁAUA_A_o!__on4)!(0.1`5%)!ɁACA߂܂!__on4)!(0.1%)!}AsAmoُAE͊Aӂ‚!zŠ!(0.1%)!A㏸!̑!(pxs)!pAAAAA!̑!(0.1`5%)!AsAi!̑!(0.1%)!قĂ6) 7) 8)!C.(}EX)ōÊ`p񍐂ĂB9)!(Ql)!}EXَe̊튯`ɃCh^V10mg^kgPo^A7.5mg^kg^9ԘAo^Ê`ɂāAO`yэïُ킪F߂ꂽB!2.{ܓ^͎𒆎~邱ƁBmֈڍs邱Ƃ񍐂ĂBn9),܂͎gpłȂ֐߃E}`̏ꍇɂ̂ݖ{܂̓^lƂƂɁA^ꍇɂ͕Kvŏ̎gpɂƂǂ߂ȂǁATdɓ^邱ƁBmɑ΂S͊mĂ炸A܂Ao^̏őʓ^ɂAdĂȕp(ǂ̕sẢ)񍐂ĂBn,,zAAF߂ꂽꍇɂ́AǏɉx�(PG) ނւ̕ϊ‚ǂyfVNILVQi[[ (COX) jQ邱ƂɂPG̐jQAPGɂ鉊ǁEMEɊoߕqpȂǂ}BCh^V̍RǍp̓AXstFju^]͂邩ɋAqhR`]ɂ܂B10)RǍp!PGEyPGI2NJgpăuWLjqX^~ACRgGȂǂɂ錌Ǔߐi𑣐iقA얞זE̊ɔoꂽPGD2AM[̃fBG[^[ƂēȂǁAǔɂPG[֗^Ă邽߁A{ɂPG̐}邱ƂōRnjʂB!Mp!OMɂPGE2AO|Ȏ̉ߒɓƔMN邽߁A{̓^ɂPG̑}ƔMƍlĂB̉߂ɂ͊֗^ĂȂB!ɍp!PG͒Ɋoe̊󐫂㏸AuWLjȂǂ̔ɍp𑝋邽߁A{ɂPG̐}ƒɌʂF߂B,ʖF!Ch^V (Indometacin)!wF![1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H - indol- 3-yl] acetic acid!w\F!qF!C19H16ClNO4!qʁF!357.79!F!Ch^V͔F`WFׂ̔Ȍ̕łB^m[AG^m[(95)̓WG`G[eɂnɂAɂقƂǗnȂB_igEtɗnB܂AɂĒFB!Z_F!155`162,,,Ch^V܃VIG 12.A. G.F Lancet, June (14), 1390 (1986)!2.Walden, R. J. et al.F Br. J. Clin. Pharmacol., 33, 241 (1992)!3.Conlin, P. R. et al.FHypertension, 36 (3), 461 (2000)!4.Boiskin, I. et al.F Annals of Internal Medicine, 106, 776 (1987)!5.Hallak, M. et al.F Obstet. Gynecol., 78 (5), 911 (1991)!6.Norton, M. E. et al.F N. EngJ. Med., 329, 1602 (1993)!7.Carol, A. M. et al.F Am. J. Obstet Gynecol, 170, 102 (1994)!8.Fejgin, M. D. et al.F American J. P., 11, 295 (1994)!9.㗲pxs;!ߕqǁ(); ];!; ɁAAcAsA啔aEMAc֊;!zŠ; ϓ;!\I!iĵ悤ȏꍇɂ͓^𒆎~邱ƁB,,҂ł͉ߓxbpɂ̉tʂ̌AENƂ̂ŁAʂJnȂǐTdɓ^邱ƁB,1.Dw!DP̓^ɊւS͊mĂȂ̂ŁADw͔DPĂ"\̂wlɂ́AÏ̗Lv댯܂Ɣfꍇɂ̂ݓ^邱ƁB!2.Y!q{kUėYN댯̂ŁADw͔DPĂ"\̂wlɂ͓^ȂƂ]܂B,,,,1.^!1.pɂ̂ݎgp邱ƁB!2.ɍۂAS𑹏邱Ƃ̂ŁATdɑ}邱ƁB}ANAo݂ꂽꍇAOZǓɓAnNꂪB!3.҂̏Ԃ�ʖ!AYXz_igE!Sodium Azulene Sulfonate!w!Sodium 1,4]dimethyl]7]isopropylazulene]3]sulfonate!\!qyѕq!C15H17NaO3SE1/2H2Forsch.A9A553i'59j!2.XؑF{ȋIvA13A116i'62j!3._JFȗՏA56A352i'62j!4.**fBbNig,,,,,,,1.dĂȊ̂銳ҁm̊}ɍx̕ǐω̂銳҂ł́A{ܓ^̊ȂAS؋Ǐ󗬂sψɂȂ邱ƂB܂ASk͂ѐS𑝂܂́AʂɁAS؋ߐS؍[ǂg傷邨ꂪƂ̕񍐂Bn!2.S[ד̂銳ҁm{܂ɂ͖[`𑣐ip̂ŁAS[ד̂銳҂ł͐S𑝉邨ꂪBn!3.ǂ̊ҁmߓx̏ꂪBn,1.{܂̓^OɁẢt̐AċzǗ̕KvȏusƁB!2.

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{܂̓^́AASASd}єAʁA܂"\ȌxѐSoʓA҂̏Ԃ�*ʖF!hu^~_(Dobutamine Hydrochloride)!wF!4-{2-[(1RS)-3-(4-Hydroxyphenyl)-1-methylpropylamino]ethyl}benzene-1,2-diolmonohydrochloride!\F!qF!C18H23NO3EHCl!qʁF!337.84!F!F`F̌̕܂͗łB!^m[ɗn₷A܂̓G^m[(95)ɂnɂAWG`G[eɂقƂǗnȂB!nti1100j͐ȂB!Z_F!188`191",*萫!ŏIipi40}1AΎx75}5A6ǰʁAhv^~_HÒt100mg͒ʏ̎sꗬʉɂ3NԈł邱ƂꂽB8j,,100mg/5mal.FActa.Cardiologica.,39(5),373,1984!2.Paulman,P.M.et al.FJAMA,264(18),2386,1990!3.caقF{Oȕ,48(5),587,1979!4.g|قFOȐf,21(8),1017,1979!5.ъقFŐVw,35(1),60!6.cBmقFՏ,3(1),31,1979!7.ʕqقFŐVw,34(11),2471,1979!8.*xmHƊ�Ӂ|t̏ɂgp邱),听!�ʖ!hu^~_(Dobutamine Hydrochloride)!w!4-o2-[i1RSj-3-(4-Hydroxyphenyl)-1-methylpropylamino]ethyl} benzene-1,2-diol monohydrochloride!q!C18H23NO3EHCl!q!337.84!Z_!188`191!!F`F̌͗̕łB!^m[ɗn₷A̓G^m[i95jɂnɂAWG`G[eɂقƂǗnȂB!nti1100j͐ȂB!\",萫8j!ŏIipi40}1AΎx75}5A6ǰʁAhv^~_HÒt100mg͒ʏ̎sꗬʉɂ3NԈł邱ƂꂽB,,hv^~_HÒt100mal.FActa.Cardiologica.,39(5),373(1984)!2.Paulman,P.M.et al.FJAMA,264(18),2386(1990)!3.caقF{Oȕ,48(5),587,(1979)!4.g,vɋLڂ̎Гɂ‚܂ĂLɂB!Th�Jo]NXz_igEa͂F̌܂͌̕łB!ɂnɂA^m[܂̓G^m[i95jɋɂ߂ėnɂAWG`G[eɂقƂǗnȂB!nti1100j͐ȂB!Z_F!210ij!ʖF!Jo]NXz_igE3919502A1090,OK,܌`EF!F̒ˉt!g!6.7`7.4!ZiHtɑ΂j!0.9`1.3,,,,,,,,,ҁmJEǓ̔Bniu҂ւ̓^v̍QƁj,1.VbN̔\邽߁A\ȖfsƁB!2.VbNɋ~}ûƂ鏀ĂƁB!3.^A҂ÂȏԂɕۂA\Ȋ�s;!; @;!**ߕq; ]2900002C1167,nC[bgח20,Eǂɂ̓-IUm[ƂāAʏ퐬l1300mgi{1.5gȀꍇ3j3ɕĐHɌo^B!ESgǂɂg̏njтɕsEْE}‚ɂ̓-IUm[ƂāAʏ퐬l110`50mgi{50`250mgjo^B!ȂANAǏɂKXB!AߕqnjQɗpꍇ́A1ō50mgi{250mgj܂łƂB,E!ESgǁiXNQAߕqnjQjɂg̏njтɕsEْE}Ǘ12,637ᒆ168i1.33jɗՏlُ̈܂ޕpF߂ĂBiFAĐRIyэĕ]Ij",,,,,,1.__on!0.1`5!C!2.__on!0.1!߂܂Eӂ‚AɁEdA㊴A炢犴!3.!0.1`5!qCEqfA!4.!0.1!֔AsAH~sUAɁAcAA₯AՁAA!5.ߕqǁ)!0.1!]AyA畆ُ튴Ag!6.zŠ!0.1!㏸A!7.̑!0.1!ASTiGOTjAALTiGPTj㏸̊�񌴐!bg񃂃fŁA-IUm[0.2ȏ̔ZxŎɍė^Ɣxᇔpx㏸Ƃ̕񍐂邪1,2)A0.04̔Zxł͔xᇔpx͏㏸ȂƂ񍐂Ă遣2)B-IUm[͔niin vitrojyѐF̎niin vivojł͕ψٌA܂A}EXi-IUm[200`2,000mg/kg/dayA78Tԍa^jAbgi-IUm[200`2,000mg/kg/dayA104Tԍa^ĵ񌴐ł́AᇗU͔F߂ȂB",qgɂ-IUm[̋z͊ɖł邪ǍZxɂ͗ǍDȗpʈˑF߂ꂽB-IUm[͔Aɂ͖ω̂ƂĔrꂸAɑӎỸtF_ƂĔrꂽ3)B,,1.ǁ4`6)!Ŏ{{ݓdӌr܂ޗՏɂāA-IUm[300mg/^ɂ茌RXe[10ȏቺǗ37.2i346/929jłAgOZCh20ȏቺǗ35.9i331/923jłBHDL-RXe[͑Ol45mg/dLɂėLӂɏ㏸B܂Aߎ_ቺB^i1N`2NA118j͑S^ɂāA肵RXe[ቺpB!2.̑̌\ɑ΂ʁ7`9)!v315ɂ‚Ď{ꂽ{ݓdӌr܂ޗՏ̌ʁAXNQAߕq咰njQɑ΂L͂ꂼ68.6i83/121jA68.4i108/158jłB,,"1.!1.ቺp10`12)!RXe[Hێ}EXAbgAETM̌RXe[LӂɒቺB̃RXe[ቺpVLDL-RXe[yLDL-RXe[̒ቺɊÂ̂łB܂AETMɂĂ̗̓LӂȒቺF߂ꂽB!2.ߎ_ቺp13)!-IUm[300mg/̓^ɂ荂NJ҂̌ߎ_LӂɒቺB!3.̑ɑ΂ʁ11,12)!RXe[Hێ惉bgAETM̊̑RXe[AɃGXe^RXe[̒ቺpBbgɂĂ͒bLӂɒቺB!4.ǂɂʁ12,14)!RXe[Hێ惉bgɂēǓ̒RXe[GXe[[LӂɘiAAV-CoARXe[AVgXtF[[Lӂɗ}邱ƂɂAǓ̃GXe^RXe[̒~ςj~ɍp邱ƂꂽB܂ARXe[HێETM̑哮Ɍ`銟daς́A̒ቺɔyB!5.‹ÏW}p15)!RXe[HێETMɃ-IUm[a^邱ƂɂAADPɂ錌‚̍őÏWLӂɗ}B!6.,ʖipj!-IUm[!\!q!C40H58O4!q!6 02.9!!F`WF̌͌̕ŁAɂyі͂ȂBAZgANz̓x[ɂn₷A^m[̓G^m[(95)ɗnɂAɂقƂǗnȂB,,,*nC[bgח20F100gE500givX`bN{gjA0.5g~200iHSj,"1.قF49{w,1990!2.яCقF50{w,1991!3.**xقFГiqgɂ򕨓ԁjA1983!4.[iقFGeriatric Medicine,20(12),2089-2096,1982!5.Ί_FVƗՏ,31(6),969-976,1982!6.YقFbƗՏ,15(8),3866-3870,1981!7.FقFYwlȂ̐E,26(5),615-617,1974!8.ؐ`قFՏƌ,61(1),222-230,1984!9.ؐ`قFՏƌ,63(5),1657-1669,1986!10.OJiقFd,11(2),411-416,1983!11.‹{قFd,10(6),1069-1075,1983!12.aqقFd,9(5),813-820,1981!13.acꐬقFGeriatric Medicine,19(8),1183-1186,1981!14.‹{قFd,10(1),137-141,1982!15.GKقFd,9(5),829-834,1981!16.YFRADIOISOTOPES,15(6),371-374,1966!17.**AFГizlpjA1975!18.cGvقF{򗝊wG,75(4),399-403,1979!19.'JaقF{򗝊wG,72(4),475-481,1976!20.ORiFp,16(6),1095-1101,1978!21.caFقF{򗝊wG,74(4),517-524,1978",**vɋLڂ̎Гɂ‚܂ĂLɂB!ː򊔎�Ǘ12,637ᒆ168i1.33jɗՏlُ̈܂ޕpF߂ĂBiFAĐRIyэĕ]Ij",,,,,,1.__on!0.1`5!C!2.__on!0.1!߂܂Eӂ‚AɁEdA㊴A炢犴!3.!0.1`5!qCEqfA!4.!0.1!֔AsAH~sUAɁAcAA₯AՁAA!5.ߕqǁ)!0.1!]AyA畆ُ튴Ag!6.zŠ!0.1!㏸A!7.̑!0.1!ASTiGOTjAALTiGPTj㏸̊�񌴐!bg񃂃fŁA-IUm[0.2ȏ̔ZxŎɍė^Ɣxᇔpx㏸Ƃ̕񍐂邪1,2)A0.04̔Zxł͔xᇔpx͏㏸ȂƂ񍐂Ă遣2)B-IUm[͔niin vitrojyѐF̎niin vivojł͕ψٌA܂A}EXi-IUm[200`2,000mg/kg/dayA78Tԍa^jAbgi-IUm[200`2,000mg/kg/dayA104Tԍa^ĵ񌴐ł́AᇗU͔F߂ȂB",qgɂ-IUm[̋z͊ɖł邪ǍZxɂ͗ǍDȗpʈˑF߂ꂽB-IUm[͔Aɂ͖ω̂ƂĔrꂸAɑӎỸtF_ƂĔrꂽ3)B,,1.ǁ4`6)!Ŏ{{ݓdӌr܂ޗՏɂāA-IUm[300mg/^ɂ茌RXe[10ȏቺǗ37.2i346/929jłAgOZCh20ȏቺǗ35.9i331/923jłBHDL-RXe[͑Ol45mg/dLɂėLӂɏ㏸B܂Aߎ_ቺB^i1N`2NA118j͑S^ɂāA肵RXe[ቺpB!2.̑̌\ɑ΂ʁ7`9)!v315ɂ‚Ď{ꂽ{ݓdӌr܂ޗՏ̌ʁAXNQAߕq咰njQɑ΂L͂ꂼ68.6i83/121jA68.4i108/158jłB,,"1.!1.ቺp10`12)!RXe[Hێ}EXAbgAETM̌RXe[LӂɒቺB̃RXe[ቺpVLDL-RXe[yLDL-RXe[̒ቺɊÂ̂łB܂AETMɂĂ̗̓LӂȒቺF߂ꂽB!2.ߎ_ቺp13)!-IUm[300mg/̓^ɂ荂NJ҂̌ߎ_LӂɒቺB!3.̑ɑ΂ʁ11,12)!RXe[Hێ惉bgAETM̊̑RXe[AɃGXe^RXe[̒ቺpBbgɂĂ͒bLӂɒቺB!4.ǂɂʁ12,14)!RXe[Hێ惉bgɂēǓ̒RXe[GXe[[LӂɘiAAV-CoARXe[AVgXtF[[Lӂɗ}邱ƂɂAǓ̃GXe^RXe[̒~ςj~ɍp邱ƂꂽB܂ARXe[HێETM̑哮Ɍ`銟daς́A̒ቺɔyB!5.‹ÏW}p15)!RXe[HێETMɃ-IUm[a^邱ƂɂAADPɂ錌‚̍őÏWLӂɗ}B!6.,ʖipj!-IUm[!\!q!C40H58O4!q!6 02.9!!F`WF̌͌̕ŁAɂyі͂ȂBAZgANz̓x[ɂn₷A^m[̓G^m[i95jɗnɂAɂقƂǗnȂB,,,nC[bg25mgF500iPTPj!*nC[bg50mgF500iPTPjA500irj,"1.قF49{w,1990!2.�Medicine,19(8),1183-1186,1981!14.‹{قFd,10(1),137-141,1982!15.GKقFd,9(5),829-834,1981!16.YFRADIOISOTOPES,15(6),371-374,1966!17.*,**vɋLڂ̎Гɂ‚܂ĂLɂB!ː򊔎�Ǘ12,637ᒆ168i1.33jɗՏlُ̈܂ޕpF߂ĂBiFAĐRIyэĕ]Ij",,,,,,1.__on!0.1`5!C!2.__on!0.1!߂܂Eӂ‚AɁEdA㊴A炢犴!3.!0.1`5!qCEqfA!4.!0.1!֔AsAH~sUAɁAcAA₯AՁAA!5.ߕqǁ)!0.1!]AyA畆ُ튴Ag!6.zŠ!0.1!㏸A!7.̑!0.1!ASTiGOTjAALTiGPTj㏸̊�񌴐!bg񃂃fŁA-IUm[0.2ȏ̔ZxŎɍė^Ɣxᇔpx㏸Ƃ̕񍐂邪1,2)A0.
04̔Zxł͔xᇔpx͏㏸ȂƂ񍐂Ă遣2)B-IUm[͔niin vitrojyѐF̎niin vivojł͕ψٌA܂A}EXi-IUm[200`2,000mg/kg/dayA78Tԍa^jAbgi-IUm[200`2,000mg/kg/dayA104Tԍa^ĵ񌴐ł́AᇗU͔F߂ȂB",qgɂ-IUm[̋z͊ɖł邪ǍZxɂ͗ǍDȗpʈˑF߂ꂽB-IUm[͔Aɂ͖ω̂ƂĔrꂸAɑӎỸtF_ƂĔrꂽ3)B,,1.ǁ4`6)!Ŏ{{ݓdӌr܂ޗՏɂāA-IUm[300mg/^ɂ茌RXe[10ȏቺǗ37.2i346/929jłAgOZCh20ȏቺǗ35.9i331/923jłBHDL-RXe[͑Ol45mg/dLɂėLӂɏ㏸B܂Aߎ_ቺB^i1N`2NA118j͑S^ɂāA肵RXe[ቺpB!2.̑̌\ɑ΂ʁ7`9)!v315ɂ‚Ď{ꂽ{ݓdӌr܂ޗՏ̌ʁAXNQAߕq咰njQɑ΂L͂ꂼ68.6i83/121jA68.4i108/158jłB,,"1.!1.ቺp10`12)!RXe[Hێ}EXAbgAETM̌RXe[LӂɒቺB̃RXe[ቺpVLDL-RXe[yLDL-RXe[̒ቺɊÂ̂łB܂AETMɂĂ̗̓LӂȒቺF߂ꂽB!2.ߎ_ቺp13)!-IUm[300mg/̓^ɂ荂NJ҂̌ߎ_LӂɒቺB!3.̑ɑ΂ʁ11,12)!RXe[Hێ惉bgAETM̊̑RXe[AɃGXe^RXe[̒ቺpBbgɂĂ͒bLӂɒቺB!4.ǂɂʁ12,14)!RXe[Hێ惉bgɂēǓ̒RXe[GXe[[LӂɘiAAV-CoARXe[AVgXtF[[Lӂɗ}邱ƂɂAǓ̃GXe^RXe[̒~ςj~ɍp邱ƂꂽB܂ARXe[HێETM̑哮Ɍ`銟daς́A̒ቺɔyB!5.‹ÏW}p15)!RXe[HێETMɃ-IUm[a^邱ƂɂAADPɂ錌‚̍őÏWLӂɗ}B!6.,ʖipj!-IUm[!\!q!C40H58O4!q!6 02.9!!F`WF̌͌̕ŁAɂyі͂ȂBAZgANz̓x[ɂn₷A^m[̓G^m[i95jɗnɂAɂقƂǗnȂB,,,nC[bg25mgF500iPTPj!*nC[bg50mgF500iPTPjA500irj,"1.قF49{w,1990!2.�Medicine,19(8),1183-1186,1981!14.‹{قFd,10(1),137-141,1982!15.GKقFd,9(5),829-834,1981!16.YFRADIOISOTOPES,15(6),371-374,1966!17.*,**vɋLڂ̎Гɂ‚܂ĂLɂB!ː򊔎�Oxidej!q!ZnO!q!81.41,,,500g,(1)1pxs; 0.1`5%; 0.1%;!ߕqǁ1; ; ; ];!ၣ1; ܉t匸A; ; ;!__on; ; ߂܂Aӂ‚AɁAsA]nlǏACAU; _Ǐi}Aoj1A1A;!zŠ; ; ጌAAAɁA; [ubNArubN;!; ; SEqfAAɁAH~sUAAS|s; ;!̑; ; ASTiGOTj㏸AALTiGPTj㏸AAl-P㏸; ;!̑; CKiCPKj㏸ALDH㏸AA_l㏸; E͊AӊAMA葫̂тꊴ; Cziނ炪j1Ȃ̋ؓɁ1A؋ْi1;!\I!1: Ǐ󂪂ꂽꍇɂ͓^𒆎~邱ƁB,,҂ɂ́A̓_ɒӂAʂ瓊^JnȂNJ҂̏Ԃ�11񓊗^̋zʁiAUCj́Ash[5mgA13񓊗^̂Ƃقړlłi}2j1)Bal.FCurr.Ther.Res.,21(5),644(1977)k197700421l!3.rcjقFGeriatr.Med.,23(3),420(1985)k198503425l!4.֌قFTher.Res.,2(2),357(1985)k198503464l!5.֌قF򗝂ƎÁA13(2),763(1985jk198503466l!6.Simpson,F.O.FDrugs,7(1),85(1974)k197400198l",`򊔎�pxs;!ߕq; zZXyfipNA`j́A݁A܁A畆ԓNƂ̂ŁÂ悤ȏꍇɂ͓^𒆎~邱ƁB;!\I,,,,,,,1.܎Fx`[̒n疌jʂ悤ɒӂ邱ƁB!2.܌tFPTP̖܂PTPV[goĕp悤w邱ƁBiPTPV[ǧɂAdspHS֎hAXɂ͐ENďcȕdĂȍǂ𕹔邱Ƃ񍐂ĂBj,,,,ĕ]ʂɂL]Ώۗ77ɂāAƂā131I-WgICbzwWƂČA84.4%i65jɗLpirA˔\Zx̌jF߂ꂽ1)B,,򗝍p1.p!{܁iEJvZj̓A~[[AveA[[Ap[[yуZ[[Lyf܂łBzyfA`AJ̈ɊpHLZXyf͈݂ł̎h~ړI環nƂA_̈ɊpHL3ނ̏yf͈ݗn͕ƂĂBi\1j!2.͂𗠕t鎎сiin vitroji\2j,,,,x`[F!A~500gAA~3kgi500g~6jASP105gi1g~105jASP1050gi0.5g~2100jASP2.1kgi1g~2100j!x`[JvZF!A~250JvZAA~1000JvZi250JvZ~4jAPTP1000JvZi10JvZ~100j,"1.`WvGcTقFଂƌA45(9),2053i1968jقk196800038l",`򊔎�211!km点F{܂͓X琸pNA`yэ׋ېyfpĂ܂B̂ߌɂAiԂɎ኱̐FϓF߂邱Ƃ܂Aiɂ͕ω܂Bl,,,,,,,,,,,,,,,,,,,,,ĕ]ʂɂS]Ώۗ77ɂāAp͔F߂ĂȂ1)B,,,,,,,!\Jn!ށ_px; pxs;!ߕq; zZXyfipNA`j́A݁A܁A畆ԓNƂ̂ŁÂ悤ȏꍇɂ͓^𒆎~邱ƁB;!\I,,,,,,,1.܎Fx`[̒n疌jʂ悤ɒӂ邱ƁB!2.܌tFPTP̖܂PTPV[goĕp悤w邱ƁBiPTPV[ǧɂAdspHS֎hAXɂ͐ENďcȕdĂȍǂ𕹔邱Ƃ񍐂ĂBj,,,,ĕ]ʂɂL]Ώۗ77ɂāAƂā131I-WgICbzwWƂČA84.4%i65jɗLpirA˔\Zx̌jF߂ꂽ1)B,,򗝍p1.p!{܁iEJvZj̓A~[[AveA[[Ap[[yуZ[[Lyf܂łBzyfA`AJ̈ɊpHLZXyf͈݂ł̎h~ړI環nƂA_̈ɊpHL3ނ̏yf͈ݗn͕ƂĂBi\1j!2.͂𗠕t鎎сiin vitroji\2j,,,,x`[F!A~500gAA~3kgi500g~6jASP105gi1g~105jASP1050gi0.5g~2100jASP2.1kgi1g~2100j!x`[JvZF!A~250JvZAA~1000JvZi250JvZ~4jAPTP1000JvZi10JvZ~100j,"1.`WvGcTقFଂƌA45(9),2053i1968jقk196800038l",`򊔎�FV!傫ij!aF6.2m1.Zx1.P񓊗^8j!Œo㌒Ni12jɃg][2.5mg󕠎ɒPo^ƂAZx͈ȉ̂悤ɐڂBTmaxihj!1.5}0.6!Cmaxing/mLj!43.2}16.1!AUC0|infingEh/mLj!2,066}1,147!t1/2ihj!68.6}36.7!ϒl}W΍!2.^!Œo㌒Ni10jɁAg][2.5mg11A^Ƃ̌򕨔Zx́A^񐔂ɂďXɏ㏸A^4TԂłقڈlɋ߂ÂB񓊗^ɑ΂4T㓊^AUC0-24iݐόWj7.2łB9j!܂AŒoҁi31jɃg][2.5mg11񔽕o^̌gtZx́A^4Tڈȍ~قڈlŐڂAԂłƍlꂽB2j!Œo㌒Ni10jɃg][2.5mg4TԔo^Ƃ̌򕨔Zx̐ځiϒl{W΍j!Œoҁi31jɃg][2.5mg𔽕^Ƃ̌gtZx̐ځiϒl{W΍Aᐔ͐}ɕ\j!2.z10j!Œo㌒Ni12jɃg][2.5mgPo^Ƃ̐΃oCIAxCreB[͖100ł,,"1.Տ1.ʗՏ2j!RGXgQ܂ɂ鎡×̂ŒoiisEĔj҂ΏۂƂʗՏɂāAuisEĔ҂ɂ鎡Ìʂ̔vɊÂʔʁA{112.5mg^̑t29.0i9/31jŁAt24TԈȏsςp54.8i17/31jłB!i2004N7܂ł̏WvG^Ԃ̒lF240AŒF1120Apj!2.IIF2Á4j!RGXgQ܂ɑ΂ĖƂȂŒoiisEĔj҂ΏۂƂIIɂāAuisEĔ҂ɂ鎡Ìʂ̔vɊÂʔʁA{112. 5mg^̑t21.1i12/57jłB!i2005N4܂ł̏WvG�to progressionFTTPj̒l̓g][Qi112.5mg^j9.4A^LVtFQi1120mg^j6.0łBTTP̃nU[h0.72i95MԁF0.62`0.83Ap

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風邪 - おつかい猫のiHerb.com(アイハーブ)で個人輸入生活

2012年3月16日 ... 製品の詳しい情報、使用方法や注意事項はメーカーの商品ページできちんと確認して 下さい。 Biotta社の ..... どうやら金属のスプーンをマヌカハニーの中に入れるとマヌカ ハニーの抗菌力が低下するらしいです。 私のほうでも .... iHerb：Zand, Zumka, Herbalozenge, Cherry Menthol Flavor, 15 Homeopathic Lozenges .... 喉が痛い時 や咳が出る時に口の中で時間をかけながらゆっくり溶かしながら舐めています。 read more

テーマ「健康」のブログ記事一覧 星の時間 奇跡の花 /ウェブリブログ

3合までの炊飯のときに使え,ちょっとお弁当に入れたいときなど,重宝します。 蒸しあがっ た ... 次男は、インフルエンザに罹りのどの痛みと咳がまだ残っています。 そこで、 ... Menthol 1% Dragons Blood 1% Cinnamon Oil 1.5% Camellia Oil 100%になる まで。 Dragons Bloodってなんだろう？ .... 10年ほど前に、妊娠中の貧血をきっかけに 栄養療法(分子整合医学)に興味を持ちはじめ、 さまざまな本や資料を読みあさりました 。 ...続きを見る ... 免疫力が低下したり、抗生物質を使った後にかかりやすいそうです。 .. .続きを ... read more

くすりのしおり

妊娠または授乳中. ・ 他に薬を .... 重症筋無力症、緑内障、肺性心、肺気腫、気管支 喘息および脳血管障害の急性期などで呼吸機能が低下している。 ・ 妊娠 ..... 発熱、 から咳がでる、呼吸困難［間質性肺炎、PIE症候群］. ・ 全身が ...... l-メントール（l- Menthol） ... read more

医薬品情報21 » 2007 » 8月 » 11

2007年8月11日 ... 添付文書に記載されている『妊婦又は妊娠していると思われる人』に対する注意は具体 的な記載はなく、『相談事項』である。 ..... ステリスコープ3W/V%液の濃度低下、実用液 の安定性は、使用環境（調製後の日数・使用頻度・温度・浸漬時間・洗浄器の種類） により大きく異なる。 ..... リナロール、カンフェン、menthol、 menthone、ペリラ アルコール、ジヒドロペルラアルコール、オイゲノール、ペリラケトン、エルショルチア ... read more